Lab studies now show that blood sugar reductions in Pycnogenol-supplemented animals are accompanied by improvements in the impaired nerve conduction velocity seen in diabetic neuropathy.24
Pycnogenol can directly oppose the excessive oxidative stress produced by diabetes, which is responsible for so much of that disease’s age-accelerating damage. ]Multiple animal studies demonstrate that Pycnogenol restores to normal the elevated markers of oxidation seen in tissues and organs of diabetic animals, while also restoring normal levels of protective intracellular antioxidant systems.25-27 This has now been shown to lead directly to reductions in inflammatory molecules, including thromboxane, a protein that triggers platelets to clump together with the potential for a dangerous clot to form.28
Finally,
Pycnogenol has been shown to inhibit alpha-glucosidase, a key intestinal enzyme that breaks down simple starch into sugars.29 Blocking alpha-glucosidase
is an effective way of slowing absorption of glucose into the bloodstream.30