SMZ-TMP Dosing

[SophieSquirrel]

I have a 40 gram baby that just came in cold and clicking. Warmed and carefully re-hydrated still minor clicking. Have some leftover SMZ-TMP - dated (filled) 6/17 (48 mg/mL)

Any thoughts on med date and dosing? I can get a call-in scrip later today. Dose now with leftover or wait until 10AM? It's 7AM now.

[Nancy in New York]

I have a 40 gram baby that just came in cold and clicking. Warmed and carefully re-hydrated still minor clicking. Have some leftover SMZ-TMP - dated (filled) 6/17 (48 mg/mL)

Any thoughts on med date and dosing? I can get a call-in scrip later today. Dose now with leftover or wait until 10AM? It's 7AM now.


I assume this is in suspension, corrrect?
If so I would toss it.
Have a script called in for Baytril in suspension.
SMZ-TMP is slower acting.

[island rehabber]

I assume this is in suspension, corrrect?
If so I would toss it.
Have a script called in the Baytril in suspension.
SMZ-TMP is slower acting.


Totally agree. SMZ-TMP is ok for soft tissue infections, etc., but Baytril is still my pneumonia drug of choice.

[SophieSquirrel]

Totally agree. SMZ-TMP is ok for soft tissue infections, etc., but Baytril is still my pneumonia drug of choice.

I found a current box of Baytril Injectable 22.7 mg/mL, not compounded in suspension. I know straight Baytril Inj can cause damage to mucosa. Approx 1 1/2 week old baby.

[Mel1959]

Yes, injectable Baytril must be diluted before given orally. Do you have any saline or lactated ringer solution to dilute with?

[Nancy in New York]

Personally I wouldn't use the injectable on a 40 gram baby
if you can have a script called in.

[SophieSquirrel]

I have many vets that can call in script but this baby is now critical. I just did Subq L Ringers as she is no longer taking fluids orally. Breathing is labored. Any thoughts on Baytril injectable Subq diluted with sterile L Ringers as a last ditch effort? Dosing?

She was out in the cold and damp prior to finders bringing in.

Warm now with hydration under skin but labored breathing.

[island rehabber]

Injectable Baytril can be given orally; it's what I have, and 22.7 is the preferred strength for small mammals.

What is the baby's weight? At this young age weight is critical for proper dosing.

[SophieSquirrel]

She's 40 grams but not taking any fluids. Lethargic, labored breathing. Subq Baytril is a last ditch effort and the only option I can see at this point.

[island rehabber]

She's 40 grams but not taking any fluids. Lethargic, labored breathing. Subq Baytril is a last ditch effort and the only option I can see at this point.

Sorry, I would not. I have never sub-q'd Baytril in 14 years. You could INJECT the first dose, according to WMB (below)

At 40g, Wild Mammal Babies recommends two doses daily of appx 0.015ml

Everyone: check my math please.

[Nancy in New York]

Sorry, I would not. I have never sub-q'd Baytril in 14 years. You could INJECT the first dose, according to WMB (below)

At 40g, Wild Mammal Babies recommends two doses daily of appx 0.015ml

Everyone: check my math please.

I get .016
This would be the loading dose, given once.
All others would be cut in half and dosed at 0.008
twice daily 12 hours apart.

EDIT: OK I see that she isn't taking oral good.

Here's the chart.
Have to go off board for ~ an hour.

https://photos.smugmug.com/photos/i-jBLvKgR/0/5bd684d3/L/i-jBLvKgR-L.jpg

[SophieSquirrel]

Sorry, I would not. I have never sub-q'd Baytril in 14 years. You could INJECT the first dose, according to WMB (below)

At 40g, Wild Mammal Babies recommends two doses daily of appx 0.015ml

Everyone: check my math please.

Since she is critical I am going to go with Subq on the first dose and hope she improves enough for oral thereafter. I am going to blend the .015 with L Ringers (sterile injectable) to cut down on tissue damage. She need more fluids anyway.

THANKS!

[island rehabber]

Thanks Nancy -- I should never try dosing when I'm in a rush -- I'm bad enough when I'm going slowly :hidechair

[SophieSquirrel]

Thanks IR and Nancy. I dosed in a blend with L Ringers. Awfully small dose to measure but luckily I have some .5 mL insulin syringes. Not hopeful with this one but I have to try everything I can. I am not home and don't have a lot of meds with me.

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[Jen413]

Prayers for this sweet baby!! :Love_Icon

[SophieSquirrel]

double post

[SophieSquirrel]

Marked improvement! Stabilized and transported to another lic rehabber.

Thanks All :hug

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