What is a safe dose of Vitamin K1 as an antidote to anti-coagulants?

[Phoxy8947]

I read in one of my rehab books that Vitamin K1 can be used as an antidote to anti-coagulant rat poisons, but it did not specify a safe dose. And I read online that giving too much can cause toxicity... Also, can it be administered orally or SQ? And is this supposed to be used in conjunction with activated charcoal??

[stepnstone]

I read in one of my rehab books that Vitamin K1 can be used as an antidote to anti-coagulant rat poisons, but it did not specify a safe dose. And I read online that giving too much can cause toxicity... Also, can it be administered orally or SQ? And is this supposed to be used in conjunction with activated charcoal??

My only use of it was a prescribed dose of 0.3 mils for an adult squirrel weighing approx 400-425 grams.

[SammysMom]

My only use of it was a prescribed dose of 0.3 mils for an adult squirrel weighing approx 400-425 grams.

Was this an injection from a vet or oral that was over the counter? I am very curious...I have been asked and never knew the correct answer.

[Phoxy8947]

My only use of it was a prescribed dose of 0.3 mils for an adult squirrel weighing approx 400-425 grams.

Yes, I'm curious to know if this was by injection, or oral administration, becuz I've read conflicting info...

[stepnstone]

Was this an injection from a vet or oral that was over the counter? I am very curious...I have been asked and never knew the correct answer.

This was oral prescribed by vet. 2-50 mg pills crushed in Nutrical
0.3 ml by mouth once daily until gone.
Vitamin K-1 can sometimes be found in health food stores OTC.
Vitamin K is easier found but not the same as Vitamin K-1 which
is what one needs for use against anti-coagulants.

[Phoxy8947]

This was oral prescribed by vet. 2-50 mg pills crushed in Nutrical
0.3 ml by mouth once daily until gone.
Vitamin K-1 can sometimes be found in health food stores OTC.
Vitamin K is easier found but not the same as Vitamin K-1 which
is what one needs for use against anti-coagulants.


Thanks!! Do u know if activated charcoal needs to be given as well?

[stepnstone]

Thanks!! Do u know if activated charcoal needs to be given as well?
I would have to guess it doesn't.
Knowing Doc, if it were needed he would have prescribed it also.

[Lighten-Up]

Thanks!! Do u know if activated charcoal needs to be given as well?

It is possible that it is not crucial that it be given for the K1 to work, however, since the purpose of activated charcoal is to bind to and escort toxins out of the body, it would make sense to me that it would be a good thing to come alongside and be helpful in the process. Only my thoughts, I am not a vet, nor do I have a lot of experience here, I'm just in the process of learning.

[Phoxy8947]

It is possible that it is not crucial that it be given for the K1 to work, however, since the purpose of activated charcoal is to bind to and escort toxins out of the body, it would make sense to me that it would be a good thing to come alongside and be helpful in the process. Only my thoughts, I am not a vet, nor do I have a lot of experience here, I'm just in the process of learning.

Thanks!! I'm trying to learn as much as I can... Even though this won't be on the license test, I still wanna learn and be the best rehabber I can

[Gray Squirrel]

This was oral prescribed by vet. 2-50 mg pills crushed in Nutrical
0.3 ml by mouth once daily until gone.
Vitamin K-1 can sometimes be found in health food stores OTC.
Vitamin K is easier found but not the same as Vitamin K-1 which
is what one needs for use against anti-coagulants.


It was said .3 ml daily is this the mixture of the two pill and Nutrical. How much Nautical were the two pills mixt with? Can vitamin K-1 be sold in all states and in pill with enough K-1 the be effective

[stepnstone]

It was said .3 ml daily is this the mixture of the two pill and Nutrical. How much Nautical were the two pills mixt with? Can vitamin K-1 be sold in all states and in pill with enough K-1 the be effective
The 0.3 dosage was within the 2 pills suspended with Nutrical by the vet, I didn't have any need to ask how he arrived at the amount of Nutrical to mix
as the purpose was to be able to get the thick mixture of K-1 through a syringe for oral administering without the unpleasant taste of the K-1.
Vitamin K-1 is not considered to be a controlled substance, whether or not you can find it in all States is not a question I can answer. Obviously there was
reason why the 2 pills were used but if using pills of K-1 were not enough to be effective why would you even think a vet would prescribe it??

[Gray Squirrel]

The 0.3 dosage was within the 2 pills suspended with Nutrical by the vet, I didn't have any need to ask how he arrived at the amount of Nutrical to mix
as the purpose was to be able to get the thick mixture of K-1 through a syringe for oral administering without the unpleasant taste of the K-1.
Vitamin K-1 is not considered to be a controlled substance, whether or not you can find it in all States is not a question I can answer. Obviously there was
reason why the 2 pills were used but if using pills of K-1 were not enough to be effective why would you even think a vet would prescribe it??

I thought the 50 ml. pills might be availed in your state without a prescription but not in all other states.

[ace]

OK. I live in Cambridge MA and have had a nice relationship with the local squirrel clans for many years. Since the pandemic we've had a rat problem, occasionally rising to rat PLAGUE, and so there are bromadioione boxes all over the neighborhood. I would like to juice up the sunflower seeds I give the squirrels with some Vitamin K, just in case. Maybe this is dumb, because the therapeutic dose for one-time bromadiolone ingestion is like 1000 times the minimum daily requirement. It might be that any safe supplement of Vit K would be negligible as prophylactic, and that daily doses at therapeutic levels would be toxic. So, first, any opinions on this? Second, making sure they have their Vit. K MDR couldn't be bad, eh? Kale? Spinach? and so on... Third, rabbits and some rodents regularly eat (some of) their feces, and one of the benefits of this is they get bacteriogenic Vit K. I can't find a reference to coprophagia among squirrels except for under Unusual circumstance, e.g., bored, in a cage. Again, any info on this? Thanks.

[TubeDriver]

I can't see a way to try to treat your friends with prophylactic vit K though food. In cases of acute poisoning with 2nd gen rodentcides, you need large doses of K1, both SC and PO, for extended periods. So vit K infused food/treats and eating poop is not going to save a squirrel that gets into those rat boxes IMHO.

What about the pandemic is causing this rat plaque in your community? Are more people putting out food for birds, squirrels and attracting the rats? Are local restaurants closing leading to rats looking for other sources of food?


OK. I live in Cambridge MA and have had a nice relationship with the local squirrel clans for many years. Since the pandemic we've had a rat problem, occasionally rising to rat PLAGUE, and so there are bromadioione boxes all over the neighborhood. I would like to juice up the sunflower seeds I give the squirrels with some Vitamin K, just in case. Maybe this is dumb, because the therapeutic dose for one-time bromadiolone ingestion is like 1000 times the minimum daily requirement. It might be that any safe supplement of Vit K would be negligible as prophylactic, and that daily doses at therapeutic levels would be toxic. So, first, any opinions on this? Second, making sure they have their Vit. K MDR couldn't be bad, eh? Kale? Spinach? and so on... Third, rabbits and some rodents regularly eat (some of) their feces, and one of the benefits of this is they get bacteriogenic Vit K. I can't find a reference to coprophagia among squirrels except for under Unusual circumstance, e.g., bored, in a cage. Again, any info on this? Thanks.