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Rhapsody
12-19-2015, 11:54 PM
My granddaughters pet bunny's is making strange sounds in his upper chest area and has barely eaten today, can someone please watch the attached video and tell me if you think he has a respiratory infection.

I have Bactrim, Cipro and Amoxi on hand.

Shewhosweptforest
12-20-2015, 12:00 AM
My granddaughters pet bunny's is making strange sounds in his upper chest area and has barely eaten today, can someone please watch the attached video and tell me if you think he has a respiratory infection.

I have Bactrim, Cipro and Amoxi on hand.

I'm not seeing a video Rhapsody:dono

Rhapsody
12-20-2015, 12:05 AM
I am working on getting the video to load........ sec.

Rhapsody
12-20-2015, 12:40 AM
Here is the video....... Figaro (the bunny)

https://www.youtube.com/watch?v=HREJ6bu3skE

Shewhosweptforest
12-20-2015, 01:17 AM
Rhapsody I really have no clue what you can give your sweet lil bun bun...he's precious and definitely is in distress....I got this from a website Medirabbit ...maybe it can help...I did see cipro mentioned :dono

Treatment

Respiratory tract diseases must be differentiated from a viral disease, a mechanical or neoplastic obstruction or hypersensitivity. If nothing is found and the presence of bacteria can be ruled out, the affected rabbit can be given antihistamines or corticosteroids (no longer than 3 to 5 days).
Successful treatment of upper respiratory infection needs to be aggressive and long. Often a combination of antibiotics is used, like oral administration of enrofloxacin or ciprofloxacin, accompanied by gentamycin based nose drops.
Trimethoprim sulfadiazine is a bactericidal antibiotic used in GI tract, respiratory and urinary infections, among others. It is efficacious against a range of bacteria that affect rabbits, including Pasteurella sp., Clostridia spp., Staphylococcus sp., Bordetella sp., etc. It can be used long term, low dose. This antibiotic often shows poor results in rabbits, and often the disease comes back worse once the treatment is stopped. This could relate to the fact that half-life of trimethoprim in a rabbit last only 40 min.
Azythromycin, a modified erythromycin, that does not show the side effects of the later in rabbits, is very efficacious in the treatment of Bordetella sp. (and so is enrofloxacin). The azythromycin doses used for rabbits (50mg/kg PO QD (SID) is much higher than that used for other small animals like cats and dogs (5-8mg/kg). Treatment lasts generally 7 days, after which an evaluation is done and eventual prolongation decided.
Cephalosporins are bactericidal broad-spectrum antibiotics used to treat skeletal, genital/urinary, skin and soft tissue bacterial and respiratory (associated with Pasteurella sp.) infections, among others. There are several generations of cephalosporin, each aiming a more or less specific group of bacteria. Although quite safe when used in injected form, this drug is potentially nephrotoxic.
The therapy against Pseudomonas sp., one of the most difficult to treat infections, must be aggressive. A sensitivity test must be done, as this bacterium is known to be multiresistant to many antibiotics. Most successful treatments involve a combination of antibiotics, for example:
Enrofloxacin + nasal drops of gentamycin;
Enrofloxacin + nebulization of amikacin (if located in the upper respiratory enrofloxacin + doxycycline;
Cephalosporin/tobramycin (both should be use in injected form only);
Azithromycin is NOT effective against Pseudomonas sp.;
Further antibiotics, safe for use in rabbits that have shown good results in the treatment of respiratory tract disease, include:
Amikacin, injected subcutaneously or nebulization, is used to treat Gram-negative bacteria,
Enrofloxacin (if injected, it can lead to the development of sterile abscesses. This can be avoided by diluting the solution with a sterile saline solution, 50:50),
Chloramphenicol (exceptionally leads to a decreased appetite),
Gentamycin, injected, drops, or nebulization, used to treat Gram-negative bacteria.
For more information, see: Antibiotics *safe* for use in rabbits
Aside a longer systemic antibiotic therapy, additional therapy comprises:
· Nasolacrimal flushes;
· Nebulization with a saline solution, mucolytics and antibiotics help bring the medication deep in the bronchia and lungs in cases of rhinitis, sinusitis or pneumonia;
· Fluid therapy and assisted force-feeding, when the rabbit refuses to drink and eat.
If the respiratory disease is accompanied by conjunctivitis and/or dacryocystitis, local antibiotic therapy (e.g. enrofloxacin, gentamycin) must accompany the treatment protocol.

Shewhosweptforest
12-20-2015, 01:31 AM
This table was from House Rabbit Society's website...I sure hope this helps:Love_Icon

Table 1. Antibiotics Used in Pet Rabbits

Antibiotic
Injectable Use?
Oral Use?
Other Use?
Risk of Antibiotic-Associated Diarrhea
Amikacin
Yes, with caution:
nephrotoxic
No oral form available
Yes, impregnated in antibiotic beads
Yes, in nebulization protocols
Low
Amoxicillin
No
No
No
High when given orally
Ampicillin
No
No
No
High when given orally
Azithromycin
No injectible form available
Yes
No
Low
Cephalosporins (Ceftazidime, Cefazolin, Ceftiofur, Cefriaxone, Cephalexin, Cephaloridine, Cephalothin)
Yes
No
No
High when given orally
CEFTIOFUR
No
No
Yes, impregnated in antibiotic beads
Low, when impregnated in antibiotic beads (bone abscess)
Chloramphenicol
Yes
Yes
Yes, ophthalmic ointment
Low
Ciprofloxacin
Yes
Yes
Yes
ophthalmic drops
Low
Clindamycin
No
No
No
High when given orally
Difloxacin
No
Yes
No
Low
Doxycycline
Yes
Yes
No
Low
Enrofloxacin
Yes
Yes
Yes; otic drops
Low
Fusidic Acid
No
No
Yes, ophthalmic ointment
Low when used as eye ointment
Gentamicin
With extreme caution:
nephrotoxic
With extreme caution:
nephrotoxic
Yes, ophthalmic drops, impregnated in antibiotic beads
Yes, in nebulization protocols
Low
Lincomycin
No
No
No
High
Marbofloxacin
No
Yes
No
Low
Metronidazole
No
Yes
Yes
Low
Oxytetracycline
Yes
No
No
Low
Oral use not recommended, calcium in GI tract inactivates drug
Penicillin (procaine)
Yes
No
No
High, when given orally or applied topically
Penicillin (procaine and benzthiazine)
Yes
No
No
High, when given orally or applied topically
Streptomycin
No, nephrotoxic
No
No
High
Sulfadimethoxine
No
Yes
No
Low
Tetracycline
Yes
No
No
Low
Oral use not recommended, calcium in GI tract inactivates drug
Tilmicosin
No
No
No
Risk of fatal adverse reaction: sudden cardiac arrest within ~30 minutes of administration
Trimethoprim/
sulphadiazine
Yes
Yes
No
Low
Trimethoprim/
sulfamethoxazole
Yes
Yes
No
Low
Tobramycin
No, nephrotoxic
No
Yes, impregnated in antibiotic beads
Yes, ophthalmic and otic drops
Low
Tylosin
Yes
No
No
Unknown

Well darn it didn't come out in table form...but you can see at the top it list the antibiotic then all the headings...oral, injectable etc. so you can look back an forth :dono here's the website...that may be the easiest way to read it :crazy1

http://rabbit.org/appropriate-use-of-antibiotics-in-rabbits-2/

TubeDriver
12-20-2015, 01:40 AM
I think that poor bunny is clearly in some type of respiratory distress. I have zero experience with rabbits but based on that video and the AB you, I would start Cipro ASAP. Cipro works really well and fast on squirrels with AP, hopefully you will see a difference in 24-48 hours if this is a bacterial lung infection. I hope some of our resident bunny experts see this and post up their thoughts but I would probably start Cipro in the meantime.

Rhapsody
12-20-2015, 01:43 AM
Is there anyone on tonight that can dose Cipro 500 mg for a bunny around 7 pounds?

pixiepoo
12-20-2015, 08:27 PM
Did you get the dosage figured out. I had a bun with chronic URI and we treated with SMZ or Baytril.