Dosing Sulfatrim (SMZ)

[Busysqrl]

Hi all,

I haven't dosed SMZ for a couple of years and can't remember if the dosing in the Wild Mammal Baby Book is the dose for twice a day. I know the dosing is twice a day but my confusion is whether the dose shown in the book is the dose for each dose. So my squirrel is 900g and I calculate the dose to be .45ml. Do I give that morning and night or divide that by 2? Am I making any sense?

Thank you!

[Nancy in New York]

Hi all,

I haven't dosed SMZ for a couple of years and can't remember if the dosing in the Wild Mammal Baby Book is the dose for twice a day. I know the dosing is twice a day but my confusion is whether the dose shown in the book is the dose for each dose. So my squirrel is 900g and I calculate the dose to be .45ml. Do I give that morning and night or divide that by 2? Am I making any sense?

Thank you!

Hi honey!!!!!!!
Yes you are making sense, let me go find my book. :grin2
What is the strength of the SMZ?

If your strength is 50 mg/ml you're correct with dosing TWICE daily the dose of .45! Total daily dose will be .9

[nchls_school]

Curious-what is SMZ for? Inquiring minds have to know and it might be useful in the future.

[Nancy in New York]

Curious-what is SMZ for? Inquiring minds have to know and it might be useful in the future.

It's a broad spectrum antibiotic which can penetrate exudates and infected tissue that other antibiotics can't. It's a good choice for skin infections abscesses or for use when the cause of the infection isn't known. It is an excellent choice to treat for enteric and urinary tract infections.

It is effective in treating coccidian toxoplasmosis, staph infections of the skin and ear, and respiratory infections, enteritis and clostridium. It can also be used to control Pasturellosis in rabbits.

Courtesy of the WMB Book. :grin2

[Busysqrl]

Thank you Nancy! OK, I'm on the right track.

In this case, we are using it for a skin staph infection that is antibiotic resistant (MRSA). The culture came back about a month ago with several choices of ABs to use and baytril was one of them so we tried that first. 4 weeks worth. Culture came back this week and it was still positive but now resistant to baytril. I hope the SMZ will kick it's butt. We are also using a topical spray called Vetericyn. The area is healing and he was on a therapudic dose, so we (the vet and vet tech) are a little confused how the bacteria mutated and became resistant to baytril. As I understand it, MRSA usually occurs when a full course of AB is not used (or less than a therapudic dose was used) and the bacteria is not completely killed, only weakened. The bacteria then somehow mutates and becomes resistant to that AB. So we are a bit mystified by what is happening especially since the area is healing. He never had any open wounds or sores, just some missing hair.

Prayers for little Magnus please :grouphug:grouphug

[nchls_school]

It's a broad spectrum antibiotic which can penetrate exudates and infected tissue that other antibiotics can't. It's a good choice for skin infections abscesses or for use when the cause of the infection isn't known. It is an excellent choice to treat for enteric and urinary tract infections.

It is effective in treating coccidian toxoplasmosis, staph infections of the skin and ear, and respiratory infections, enteritis and clostridium. It can also be used to control Pasturellosis in rabbits.

Courtesy of the WMB Book. :grin2

Thank you for the answer and knowing this could come in handy some day.

[TubeDriver]

Some of the bacteria could have migrated to somewhere the AB could not reach or work? Another possibility is that the baytril was old or had been compromised somehow (temps, light exposure etc). Although he does not have an open wound, the bacteria could be multiplying under the skin and into muscle/fat, keep a sharp lookout for swelling and other signs of infection.

Good luck, MRSA can be very difficult to treat. Hang in there little Magnus!:grouphug



Thank you Nancy! OK, I'm on the right track.

In this case, we are using it for a skin staph infection that is antibiotic resistant (MRSA). The culture came back about a month ago with several choices of ABs to use and baytril was one of them so we tried that first. 4 weeks worth. Culture came back this week and it was still positive but now resistant to baytril. I hope the SMZ will kick it's butt. We are also using a topical spray called Vetericyn. The area is healing and he was on a therapudic dose, so we (the vet and vet tech) are a little confused how the bacteria mutated and became resistant to baytril. As I understand it, MRSA usually occurs when a full course of AB is not used (or less than a therapudic dose was used) and the bacteria is not completely killed, only weakened. The bacteria then somehow mutates and becomes resistant to that AB. So we are a bit mystified by what is happening especially since the area is healing. He never had any open wounds or sores, just some missing hair.

Prayers for little Magnus please :grouphug:grouphug

[Busysqrl]

Some of the bacteria could have migrated to somewhere the AB could not reach or work? Another possibility is that the baytril was old or had been compromised somehow (temps, light exposure etc). Although he does not have an open wound, the bacteria could be multiplying under the skin and into muscle/fat, keep a sharp lookout for swelling and other signs of infection.

Good luck, MRSA can be very difficult to treat. Hang in there little Magnus!:grouphug

Thank you TubeDriver. I use tablet Baytril and it was brand new so I don't think it was compromised, although you never know. Yeah, no problem with keeping an eye out. I probably drag that poor baby out of his nest box and look him over thoroughly about 3 times a day. Poor little guy. I know, MRSA is a beast. I've been doing a little research on it today and it's quite nasty.

I ordered a medicinal honey called Manuka honey. It's been used for thousands of years and there have even been scientific studies done on this particular type of honey. It is very effective on some strains of MRSA. I will be using it topically along with several other things.

I also ordered some Vetri-DMG which I haven't used for a couple of years to help support his immune system. ANYTHING to help him fight this crazy infection.

The good news is that the fur is growing back so we are making progress. I just want to make sure we get it completely squashed! Thanks for the good thoughts for my sweet little Magpie :)

[TubeDriver]

Hair growth is a very good sign!:thumbsup



Thank you TubeDriver. I use tablet Baytril and it was brand new so I don't think it was compromised, although you never know. Yeah, no problem with keeping an eye out. I probably drag that poor baby out of his nest box and look him over thoroughly about 3 times a day. Poor little guy. I know, MRSA is a beast. I've been doing a little research on it today and it's quite nasty.

I ordered a medicinal honey called Manuka honey. It's been used for thousands of years and there have even been scientific studies done on this particular type of honey. It is very effective on some strains of MRSA. I will be using it topically along with several other things.

I also ordered some Vetri-DMG which I haven't used for a couple of years to help support his immune system. ANYTHING to help him fight this crazy infection.

The good news is that the fur is growing back so we are making progress. I just want to make sure we get it completely squashed! Thanks for the good thoughts for my sweet little Magpie :)